Characterizing viral vectors with NanoSight Pro & Zetasizer Advance

This collection of eight application notes illustrates how NanoSight Pro and Zetasizer Advance are utilized for the general characterization of viral vectors and highlights the capabilities of its specialized fluorescence mode for gaining a deeper understanding of lentivirus and MVA characteristics.

The results demonstrate that NanoSight Pro, particularly its specialized fluorescence mode, provides detailed insights into viral vector characterization. It reveals critical parameters such as size, titer, and labeling efficiency for various applications, including the detection of vector membranes, specific markers, and cargo. This comprehensive analysis enhances our understanding of viral vector characteristics and offers valuable insights for optimization processes. 

You’ll also learn how nanoparticle tracking and fluorescence detection capabilities of NanoSight Pro complement dynamic light scattering technology, by providing higher resolution size data and particle concentration, making it ideal for complex, polydisperse samples.