After thoroughly evaluating several hundred proposals, our team of scientists has selected the top ten scientific papers submitted for the Malvern Panalytical Scientific Award, as well as the overall winner.
Our shortlist can be found in the table below – congratulations to our top ten!
The award winner for 2024
We are excited to announce that the winner of the Malvern Panalytical Scientific Award 2024 is Lei Gao of Peking University!
Lei’s paper is on ‘Boosting lithium ion conductivity of antiperovskite solid electrolyte by potassium ions substitution for cation clusters’ published in Nat Commun 14, 6807 (2023).
Read the paper here: Boosting lithium ion conductivity of antiperovskite solid electrolyte by potassium ions substitution for cation clusters
The 2024 shortlist
We sincerely thank all the authors who submitted their papers and congratulate everyone shortlisted below. The order in the table is random and does not represent any scoring or ranking results.
| Author | Title of Paper | Product |
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*Winner*Lei Gao Peking University, Beijing, China | Boosting lithium ion conductivity of antiperovskite solid electrolyte by potassium ions substitution for cation clusters This study enhances lithium-ion conductivity in antiperovskite solid electrolytes via potassium substitution. The modified electrolyte improves ionic transport, stabilizes the cubic phase, and enables high-performance solid-state batteries. | Empyrean |
Marko Dunatov Ruđer Bošković Institute, Zagreb, Croatia | Multi-stimuli responsive (L-tartrato)oxovanadium(V) complex salt with ferroelectric switching and thermistor properties A (L-tartrato)oxovanadium(V) complex salt exhibits ferroelectric switching, thermistor behavior, and photoresponsiveness. Its humidity- and temperature-driven transformations make it promising for device applications. | Empyrean |
Wojciech Piotrowski Institute of Low Temperature and Structure Research, Polish Academy of Sciences, Wrocław, Poland | Mn5+ Lifetime-Based Thermal Imaging in the Optical Transparency Windows Through Skin-Mimicking Tissue Phantom Mn⁵⁺/Er³⁺ co-doped nanothermometers offer enhanced near-infrared emission and extended lifetimes for precise deep-tissue thermal mapping. A custom instrument enables 2D imaging, advancing preclinical applications. | X'Pert3 MRD |
Michel Ammendola The Pennsylvania State University, University Park, Pennsylvania, United States | Evaluation of chromium coatings deposited by standard and bipolar high-power impulse magnetron sputtering (HiPIMS & B-HiPIMS) for nuclear power applications This study compares chromium coatings on Zircaloy-4 deposited via DCMS, HiPIMS, and B-HiPIMS for nuclear fuel applications. HiPIMS and B-HiPIMS outperform DCMS, showing superior microstructure, lower residual stress, and a tenfold reduction in autoclave weight gain at 360 °C, indicating better performance in PWR environments. | Empyrean |
Hanjun Zou Chongqing University, Chongqing, China | Relationship between defect and strain in oxygen vacancy-engineered TiO2 towards photocatalytic H2 generation Photocatalytic H₂ generation converts solar energy into renewable fuel, with oxygen vacancy engineering as a promising strategy. However, the interplay of defects and strain remains unclear. Using TiO₂ as a model, this study reveals that optimal H₂ production (788 μmol g⁻¹ h⁻¹) occurs with high oxygen vacancy concentration but minimal strain. Results show defects, not strain, primarily enhance performance, supported by theoretical and experimental analyses. | Empyrean |
Luca Casula University of Cagliari, Cagliari, Sardinia, Italy | Development of Nanofibers with Embedded Liposomes Containing an Immunomodulatory Drug Using Green Electrospinning Green electrospinning is used to embed liposomes with an immunomodulatory drug into nanofibers, offering a controlled-release system with pharmaceutical potential. | Zetasizer Ultra (Red) |
Luca Morici University of Geneva, Geneva, Switzerland | Nanocrystal-chitosan particles for intra-articular delivery of disease-modifying osteoarthritis drugs Osteoarthritis lacks effective treatments due to its degenerative nature. Kartogenin promotes cartilage repair but has poor solubility. To enhance its therapeutic effect, we developed a nanocrystal-chitosan microsphere system using wet milling and spray drying. This resuspendable powder enables intra-articular injection, improving solubility, stability, and controlled release in synovial fluid. The system was non-toxic to human synoviocytes and demonstrated cartilage retention ex vivo, showing promise for osteoarthritis therapy and scale-up production. | Mastersizer 3000+ Lab |
Julia Werner Heidelberg University Hospital, Heidelberg, Germany | Improved pharmacokinetics and enhanced efficacy of the vancomycin derivative FU002 using a liposomal nanocarrier Antibiotic resistance limits treatment options, but the vancomycin derivative FU002 shows strong activity against Gram-positive bacteria. To enhance its pharmacokinetics, FU002 was encapsulated in PEGylated liposomes, prolonging circulation in Wistar rats without cytotoxicity. Encapsulation maintained antimicrobial potency and improved therapeutic efficacy in a Galleria mellonella infection model. | Zetasizer Advance Range |
Prem Singh Oregon State University, Corvallis, Oregon, United States | Palladium Nanocapsules for Photothermal Therapy in the Near-Infrared II Biological Window The study presents a bimetallic palladium nanocapsule (Pd Ncap) for plasmonic photothermal therapy (PPTT), capable of absorbing both NIR-I and NIR-II light. Functionalized with Herceptin (Pd Ncap-Her), it targets breast cancer cells, inducing over 98% cell death with low laser power and nanoparticle concentration. The Pd Ncap demonstrates high photothermal stability, ROS scavenging ability, and effective tumor ablation in vivo, making it a promising candidate for cancer therapy. | NanoSight range |
Beatriz Dias Barbieri Imperial College London, United Kindom | The role of helper lipids in optimising nanoparticle formulations of self-amplifying RNA This study explores how helper lipids (DSPC, DOPC, DOPE) and ionisable lipids (MC3, C12–200) affect the stability and effectiveness of self-amplifying RNA (saRNA) vaccines. DSPC with C12–200 provided the best stability and durable expression in skin explants. C12–200 also improved protein expression and immune responses to a SARS-CoV-2 vaccine, highlighting the importance of helper lipids in optimizing saRNA vaccine performance. | Zetasizer Ultra (Red) |
2023 results
We sincerely thank all the authors who submitted their papers and congratulate everyone shortlisted below. The order in the table is random and does not represent any scoring or ranking results.
The authors from this list will be presenting their work in our 2024 Ask an Expert webinar program!
| Author | Title of Paper | Product | Research link |
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*Winner* Rohan Pokratath
University of Basel, Basel, Switzerland |
Mechanistic Insight into the Precursor Chemistry of ZrO2 and HfO2 Nanocrystals; towards Size-Tunable Syntheses
Delves into the precursor chemistry of ZrO 2 and HfO 2 nanocrystals, aiming for controllable syntheses of varying sizes. It explores the mechanisms behind their formation, offering insights for tailored and size-tunable production. |
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Shardul Pandit
TU Wien, Vienna, Austria |
Impact of AlN Seed Layer on Microstructure and Piezoelectric Properties of YxAl1−xN (x = 15%) Thin Films
Investigates the influence of an AlN seed layer on the microstructure and piezoelectric properties of YxAl1−xN (x = 15%) thin films. The study delves into the nuanced interactions between the seed layer and thin films, shedding light on how these factors impact material characteristics. Insights gained from this research contribute to the enhancement of piezoelectric performance in thin films, offering valuable implications for diverse applications. |
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Abimannan Sethurajaperumal
SRM Institute of Science and Technology, Kattankulathur, Chengalpattu, Tamil Nadu, India |
High-Quality and Efficient Liquid-Phase Exfoliation of Few-Layered Graphene by Natural Surfactant
Achieves superior liquid-phase exfoliation of few-layered graphene utilizing a natural surfactant. The method ensures high quality and efficiency in the exfoliation process, opening new avenues for applications in various industries. This innovative approach marks a significant stride in advancing graphene-based materials through sustainable and effective methodologies. |
High-Quality and Efficient Liquid-Phase Exfoliation of Few-Layered Graphene by Natural Surfactant |
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Silang Zhou
University of Groningen |
Thin films of the α-quartz S ixG e(1-x)O2 solid solution
Delves into thin films of the α-quartz SiₓGe(1-x)O 2 solid solution. Investigating the material properties of this composition, the study explores the intricate relationship between silicon (Si) and germanium (Ge) within the α-quartz structure. Through the deposition of thin films, the researchers aim to unravel the unique characteristics and potential applications of this solid solution, offering insights into its structural and functional attributes. |
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Steven Street
University of Victoria, Victoria, British Columbia, Canada |
Length-Controlled Nanofiber Micelleplexes as Efficient Nucleic Acid Delivery Vehicles
Introduces "Length-Controlled Nanofiber Micelleplexes," advancing nucleic acid delivery. Engineered for efficiency, these nanofiber structures promise breakthroughs in targeted drug delivery and therapeutic applications, marking a significant stride in the field of nanomedicine. |
Length-Controlled Nanofiber Micelleplexes as Efficient Nucleic Acid Delivery Vehicles |
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Rosy Ghanem
INSERM U1078, Brest, France |
Gene transfection using branched cationic amphiphilic compounds for an aerosol administration in cystic fibrosis context
Explores gene transfection employing branched cationic amphiphilic compounds. This novel approach aims for aerosol administration, particularly relevant in the context of cystic fibrosis. The study investigates the potential of this technique to enhance therapeutic outcomes for individuals with cystic fibrosis, offering a promising avenue for targeted gene delivery. |
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Muhammed Awad
University of South Australia, Adelaide, Australia |
Gallium Protoporphyrin Liquid Crystalline Lipid Nanoparticles: A Third-Generation Photosensitizer against Pseudomonas aeruginosa Biofilms
Introduces Gallium Protoporphyrin Liquid Crystalline Lipid Nanoparticles as a third-generation photosensitizer combating Pseudomonas aeruginosa biofilms. This groundbreaking approach holds promise for enhanced efficacy in biofilm eradication, marking a significant stride in antimicrobial strategies. |
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Alex Mathers
UCT, Prague (VŠCHT), Prague, Czech Republic |
API solubility in semi-crystalline polymer: Kinetic and thermodynamic phase behavior of PVA-based solid dispersions
Investigates the solubility of an Active Pharmaceutical Ingredient (API) in a semi-crystalline polymer, specifically Polyvinyl Alcohol (PVA). The study explores both kinetic and thermodynamic aspects of phase behavior in PVA-based solid dispersions. Understanding the interplay between the API and polymer at a molecular level provides valuable insights for optimizing drug delivery systems. |
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Usri Ibrahim
University of KwaZulu-Natal, Durban, South Africa |
Dual acting acid-cleavable self-assembling prodrug from hyaluronic acid and ciprofloxacin: A potential system for simultaneously targeting bacterial infections and cancer
Introduces a dual-acting acid-cleavable self-assembling prodrug synthesized from hyaluronic acid and ciprofloxacin. This innovative system holds promise for concurrent targeting of bacterial infections and cancer, presenting a potential breakthrough in the field of therapeutic interventions. The synergistic properties of hyaluronic acid and ciprofloxacin offer a versatile approach for addressing these distinct health challenges within a single, efficient platform. |
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Damian Wlodarczyk
Institute of Physics Polish Academy of Sciences, Warsaw, Poland |
Synthesis Attempt and Structural Studies of Novel A2CeWO6 Double Perovskites (A2+ = Ba, Ca) in and outside of Ambient Conditions
Novel A 2 CeWO 6 double perovskites (A2+ = Ba, Ca) are synthesized and structurally studied both in and outside of ambient conditions. The investigation delves into the synthesis attempts and explores the unique structural characteristics of these compounds, providing valuable insights into their properties. |
2022 results
We sincerely thank all the authors who submitted their papers and congratulate everyone shortlisted below. The order in the table is random and does not represent any scoring or ranking results.
The authors from this list will be presenting their work in our 2023 Ask an Expert webinar program!
| Author | Title of Paper | Link |
|---|---|---|
| *Winner* Grace A. Pan, Harvard University, Cambridge, MA, USA | Superconductivity in a quintuple-layer square-planar nickelate
Identifies square-planar nickelates as a new family of superconductors that can be tuned via doping and dimensionality by reporting synthesis of the quintuple-layer (n=5) Nd6Ni5O12, in which optimal cuprate-like electron filling (d8.8) is achieved without chemical doping. | Nature Materials, VOL 21, February 2022, 160–164 |
| Jian Peng, Huazhong University of Science and Technology, Wuhan 430074, P. R. China, and University of Wollongong, North Wollongong, NSW 2522, Australia | Defect-free-induced Na+ disordering in electrode materials Explores high-performance electrode materials, specifically investigating a very simple and universally applicable self-healing method to prepare defect-free Prussian blue analogs (PBAs) that reach theoretical capacity as cathode materials for sodium-ion batteries (SIBs). | Energy Environ. Sci., 2021, 14, 3130 |
| Tereza Košutova, Charles University, Prague, Czech Republic | Thermally-driven morphogenesis of niobium nanoparticles as witnessed by in-situ x-ray scattering Prepared highly porous structures consisting of niobium nanoparticles (Nb NPs) using magnetron sputtering and inert gas aggregation. Alongside the thermally-driven evolution of nanoparticle morphology, the microstructural genesis was probed in situ by X-ray diffraction for the temperature range up to 800 °C. | Materials Chemistry and Physics 277 (2022) 125466 |
| Lu Hou, Dalian University of Technology, Dalian 116024, P. R. China | Selective Synthesis of Carbon Nanorings via Asymmetric Intramicellar Phase-Transition-Induced Tip-to-Tip Assembly Reports precise synthesis of carbon nanorings with well-defined morphology and tunable thickness, based on asymmetric intramicellar phase-transition-induced tip-to-tip assembly via mixing hydrophobic long-chain octadecanol and block copolymer F127. This orientational self-assembly depends on the hydrophobicity difference of the intermediate’s surface, which triggers directional interactions that surpass the entropy cost of undesired connections and help assemble intermediates into defined ringlike structures. | ACS Cent. Sci. 2021, 7, 1493−1499 |
| Prince K. Verma, University of Virginia, Charlottesville, Virginia 22904, United States | Controlling Polymorphism and Orientation of NU-901/NU-1000 Metal−Organic Framework Thin Films Utilized self-assembled monolayers and crystal engineering to control the polymorphism and orientation of NU-901/NU-1000 thin films. The fabrication of thin films of NU-901 and NU-1000 is carried out via a solvothermal method by functionalizing the substrate with carboxyl (−COOH) tail groups. | Chem. Mater. 2020, 32, 10556−10565 |
| Nitish Kumar, IIT Jammu, Jammu and Kashmir, 181221, India | Block copolymer-assisted synthesis of VO2 (B) microflowers for supercapacitor applications Explores nanoporous metal oxides in energy storage applications. The study synthesized VO2 (B) microflowers with a stable phase and tailored porous structures, utilizing block copolymers to achieve excellent supercapacitor performance. | https://doi.org/10.1039/d1cc05978e |
| Nazeer Hasan, Defence Research and Development Organisation, Delhi 110054, and School of Pharmaceutical Education and Research, New Delhi 110062, and School of Pharmaceutical sciences, Delhi Pharmaceutical Science and Research University, Delhi 110017, India | Intranasal delivery of Naloxone-loaded solid lipid nanoparticles as a promising simple and non-invasive approach for the management of opioid overdose Overcomes limitations of naloxone when administered orally for opioid overdose. The team developed intranasal solid-lipid nanoparticles found to result in higher drug release and superior drug uptake by nasal membrane throughout in vitro, ex vivo, and in vivo experiments. | International Journal of Pharmaceutics, Volume 599, 15 April 2021, 120428 |
| Giuseppe Battaglia, Università degli studi di Palermo, 90128 Palermo, Italy | Analysis of particles size distributions in Mg(OH)2 precipitation from highly concentrated MgCl2 solutions Sheds light on characteristics of produced Mg(OH)2 particles recovered via precipitation, and dependence upon the reacting conditions. Particles were analyzed by laser static light scattering, with and without an anti-agglomerant treatment based on ultrasounds and addition of a dispersant. | Powder Technology, Volume 398, January 2022, 117106 |
| Ramón Andrés Pineda-Álvarez, Facultad de Estudios Superiores Cuautitlán-Universidad Nacional Autónoma de México, Carretera Cuautitlán-Teoloyucan, 54714 Cuautitlan Izcalli, Mexico | Development and Characterization of Starch/Gelatin Microneedle Arrays Loaded with Lecithin–Gelatin Nanoparticles of Losartan for Transdermal Delivery Aimed to develop and characterize biodegradeable polymeric microneedle arrays loaded with (i) losartan potassium powder and (ii) nanoparticles loaded with losartan potassium dispersed in polymeric matrix (starch/gelatin) as innovative pharmaceutical forms for blood pressure control. | Journal of Pharmaceutical Innovation volume 17, pages71–84 (2022) |
| Dan Trunov, University of Chemistry and Technology, 166 28 Prague Czech Republic | Ambient-temperature porogen-free method for preparation of silica-based macroporous materials Focuses on synthesis of silica-based microporous aggregates composed of silica nanoparticles using template-free method. The results confirm possibility of tailoring pore size distribution simply by using primary particles of various sizes. The application of prepared aggregates was demonstrated by immobilization of urease from Canavalia ensiformis, resulting in high enzyme activity compared with free enzymes. | Colloids and Surfaces A: Physicochemical and Engineering Aspects, Volume 634, 5 February 2022, 128033 |